We – EPG Group the bigge EPT gearbox & motors , vee pulleys, timing pulleys, couplings and gears manufacturing unit in China with 5 diverse branches. For more specifics: Cellular/whatsapp/telegram/Kakao us at: 0086~13083988828 13858117778 0571 88828
Manufacturing facility EPT twenty five-hydroxy Cholesterol CAS 2140-46-7 in bulk inventory ninety nine% be EPT price
Introduction:
one.Product title:twenty five-hydroxy Cholesterol
EPT identify:3,4-Caranediol,(+)- (8CI)Bicyclo[4.1.]heptane-3,4-diol, 3,7,7-trimethyl-, [1S-(1a,3a,4b,6a)]-
(+)-3,4-Caranediol[1S-(1a,3a,4b,6a)]-3,7,7-Trimethylbicyclo[4.1.]heptane-3,4-diol
two.CAS NO 2140-46-7
three.Specification:99%
4.MF:C27H46O2
five.MW:402.65
six.Item Description:
25-hydroxy Cholesterol is a facet-chain substituted oxysterol derived from dietary cholesterol that inhibits the cleavage of sterol regulatory factor binding proteins (SREBPs) to suppress endogenous cholesterol synthesis in various mobile types. It has been implicated in a assortment of metabolic functions such as cholesterol homeostasis and atherosclerosis as nicely as antitumor actions as it has been demonstrated to induce apoptosis by way of down-regulation of Bcl-2 expression and activation of caspases. Immunomodulating abilities have also been observed as the oxysterol can act as a LXR-R EPT ligand coupling cholesterol synthesis to T cell proliferation, can decrease (EC50 ~ sixty five nM) IgA creation by B cel EPT in reaction to IL-2, and can suppress differentiation of monocytes into macrophages.
Specification:
| Product | Regular | Te EPT Results | |
| Identification | A.H-NMR:Comply with the structure | Complies | |
| B.LC-MS:Comply with the structure | Complies | ||
| C.The IR spectrum of sample must be equivalent with that of reference normal | Complies | ||
| D.HPLC-ESI-MS | Complies | ||
| The retention time of the key peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Normal preparing, as acquired in the Assay. | |||
| Crystallinity | meets the requirements. | Complies | |
| Decline on drying | ≤2.% | .19% | |
| Heavy metals | ≤10 ppm | <10ppm | |
| Drinking water | ≤1.% | .ten% | |
| Sulphated ash | ≤0.5%, determined on 1. g. | .01% | |
| Related substances | Unspecified impurities: for each impurity | ≤0.10% | <0.10% |
| Overall Impurity | ≤0.5% | .18% | |
| Purity | ≥99.% | ninety nine.70% | |
| Assay | 99.%~one hundred and one.% (anhydrous material). | ninety nine.eighty% | |
| Microbiological Investigation | |||
| Total plate depend | ≤1000cfu/g | Complies | |
| Yea EPT and Moulds | ≤100cfu/g | Complies | |
| E. Coli. | Absent | Unfavorable | |
| Salmonella | Absent | Adverse | |
| S.aureus | Absent | Adverse | |
| Storage | Preserve in properly-shut, gentle-resistant and airtight containers. | Complies | |
We – EPG Group the bigge EPT gearbox & motors , vee pulleys, timing pulleys, couplings and gears factory in China with 5 diverse branches. For far more details: Mobile/whatsapp/telegram/Kakao us at: 0086~13083988828 13858117778 0571 88828 The use of authentic equipment manufacturer’s (OEM) component quantities or emblems , e.g. CASE® and John Deere® are for reference functions only and for indicating product use and compatibility. Our business and the listed substitution components contained herein are not sponsored, authorized, or created by the OEM.
